UK Skin Cancer and Melanoma Patients

[sadsam]

Hi

Just been sent this link http://www.prokerala.com/news/articles/a83874.html

[danensis]

Thanks for posting that, it got me looking at J Med Chem again, and the next article was equally interesting:

"Disulfiram Facilitates Intracellular Cu Uptake and Induces Apoptosis in Human Melanoma Cells ... The alcohol-abuse deterrent disulfiram (DSF) is shown to have a highly selective toxicity against melanoma ... Melanoma cell lines derived from different stages (radial, vertical, and metastatic phase) were all sensitive to DSF treatment in vitro; melanocytes were only slightly affected. ..."

Of course in-vitro tests don't always translate to the clinic........

J. Med. Chem. is a highly regarded peer-reviewed journal.